Vol. 1, Issue 2, Part A (2025)

High-risk occupations such as firefighting, mining, construction, military operations, and emergency response place significant physiological and biomechanical demands on workers, making accurate fitness-for-work assessment essential for ensuring safety, performance efficiency, and long-term occupational health. Traditional screening methods used in many organizations rely mostly on medical checklists, generalized physical tests, or subjective evaluation, which fail to capture the complex interaction between physiological readiness, functional capacity, fatigue patterns, and real-world task performance. This study developed and evaluated a comprehensive multidimensional assessment framework integrating cardiovascular indicators, neuromuscular strength measures, autonomic regulation parameters, metabolic fatigue markers, and functional movement evaluations to more accurately assess work readiness among individuals employed in high-risk environments. A cross-sectional analysis was conducted using validated physiological tools—including VO₂max testing, heart-rate variability monitoring, grip strength profiling, lactate threshold evaluation, and electromyographic fatigue analysis—combined with kinematic movement screening using wearable sensor systems. The results showed that high performers consistently exhibited superior aerobic capacity, greater neuromuscular strength, more balanced autonomic regulation, and more efficient movement patterns compared to moderate performers. Regression modeling further demonstrated that VO₂max and heart-rate variability were strong predictors of functional performance, reinforcing the importance of integrating physiological and biomechanical indicators into workforce evaluation. The findings suggest that multidimensional assessments provide a more accurate representation of worker capability, contributing to improved risk mitigation, enhanced task allocation, and reduced injury rates in high-hazard sectors. The study concludes that adopting holistic fitness-for-work evaluation models can significantly strengthen workplace safety protocols, guide personalized conditioning programs, and support evidence-based decision-making in occupational health. Additionally, the research emphasizes the value of implementing targeted physical training, ongoing functional screening, ergonomic improvements, and continuous physiological monitoring to maintain optimal worker readiness. This multidimensional approach ultimately offers a scientifically grounded method for organizations seeking to enhance worker performance, reduce incidents, and promote a healthier, more resilient workforce in challenging occupational settings.